Located in Tokyo, Japan the orphanage was a gated, two story building. It appeared designed for young children to live in with it being colored green, red and blue on the exterior.
Inside there was an open stairway featuring wooden appearing panels on the walls, and balusters supporting the handrail. Natural light was provided by a circular window.
Overall the interior was in a similar theme with an upper room consisting of a vibrant decor including child like arts and crafts as well as being what appeared as a general play area. The walls and shelves of this room were decorated in winter Christmas related designs, with a pink and green rectangular carpet. There was a balcony area on the second floor used to air laundry.
The orphanage was well maintained with greenery on the premises from bushes to trees.
The orphanage took in children some who had been mistreated by their parents and maintained an ethos that all those at the orphanage were one large family. When Yu arrived, "welcome" was written in Japanese on the activity board.
- Hyakuya Orphanage Director
- Yūichirō Hyakuya (Former resident)
- Mikaela Hyakuya (Former resident)
- Akane Hyakuya
- Kōta Hyakuya
- Chihiro Hyakuya
- Ako Hyakuya
- Fumie Hyakuya
- Taichi Hyakuya
As the apocalypse is underway with adults dying all around, Yu, Mika and Akane run back to the building with other orphans and hide themselves on the second floor. They huddle in the dark until vampires enter the room by the door, and by shattering a glass window on the balcony where the orphans are taken from the orphanage to Sanguinem.
It is remembered by Yu of how he first arrived at the orphanage, and introduced by the director to the other children the playroom was where he first met Mika. After being greeted by other children who wanted to share accounts of how they became orphans they then notice the orphanage director suddenly die.